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Together Mental Health Clinic is Now REMS Certified to Provide SPRAVATO® (esketamine) CIII Nasal Spray Medication for Adults with Treatment-Resistant Depression.
Get to Know Spravato®
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Studied in adults with treatment-resistant depression*
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Nasal spray you self-administer under the supervision of a healthcare provider
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Taken with an oral antidepressant
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Greater reduction of depression symptoms at four weeks‡ (compared to those who received a placebo and oral antidepressant)
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After 16 weeks of therapy, those patients who stayed on SPRAVATO®† did better than those who stopped therapy
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Tell your healthcare provider if you have a history of drug or alcohol abuse
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After you take SPRAVATO®, a healthcare provider will monitor you for at least two hours during the observation period for possible side effects. More About Side Effects
Spravato® Safety and Tolerability
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SPRAVATO® nasal spray was evaluated for safety in both short- and long-term clinical trials of adults diagnosed with treatment-resistant depression
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Do not take SPRAVATO® if you have a blood vessel disease (aneurysm), an abnormal connection between your blood vessels (arteriovenous malformation), a history of bleeding in the brain or are allergic to esketamine, ketamine or any of the ingredients in SPRAVATO®. Talk to your healthcare provider to learn more.


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